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pentobarbital will lessen the extent or outcome of cevimeline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Mysterious.pentobarbital increases effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism. Use Warning/Watch. Coadministration of ifosfamide with CYP2B6 inducers may increase metabolism of i